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Structure and dynamics of the DNA hairpins formed by tandemly repeated CTG triplets associated with myotonic dystrophy.

Anomalous expansion of the DNA triplet (CTG)n causes myotonic dystrophy. Structural studies have been carried out on (CTG)n repeats in an attempt to better understand the molecular mechanism of repeat expansion. NMR and gel electrophoretic studies demonstrate the presence of hairpin structures for (...

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Published in:Nucleic Acids Res
Main Authors: Mariappan, S V, Garcoa, A E, Gupta, G
Format: Artigo
Language:Inglês
Published: Oxford University Press 1996
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145682/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8604323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.4.775
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