A Drosophila Model of Multiple Endocrine Neoplasia Type 2

Dominant mutations in the Ret receptor tyrosine kinase lead to the familial cancer syndrome multiple endocrine neoplasia type 2 (MEN2). Mammalian tissue culture studies suggest that Ret(MEN2) mutations significantly alter Ret-signaling properties, but the precise mechanisms by which Ret(MEN2) promot...

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Autors principals: Read, Renee D., Goodfellow, Paul J., Mardis, Elaine R., Novak, Nancy, Armstrong, Jon R., Cagan, Ross L.
Format: Artigo
Idioma:Inglês
Publicat: Copyright © 2005 by the Genetics Society of America 2005
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456812/
https://ncbi.nlm.nih.gov/pubmed/15965261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.038018
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