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Genome-Wide Synthetic Lethal Screens Identify an Interaction Between the Nuclear Envelope Protein, Apq12p, and the Kinetochore in Saccharomyces cerevisiae

The maintenance of genome stability is a fundamental requirement for normal cell cycle progression. The budding yeast Saccharomyces cerevisiae is an excellent model to study chromosome maintenance due to its well-defined centromere and kinetochore, the region of the chromosome and associated protein...

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Main Authors: Montpetit, Ben, Thorne, Ken, Barrett, Irene, Andrews, Kim, Jadusingh, Ravi, Hieter, Phil, Measday, Vivien
Format: Artigo
Jezik:Inglês
Izdano: Copyright © 2005 by the Genetics Society of America 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456766/
https://ncbi.nlm.nih.gov/pubmed/15998715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.045799
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