Desialylation of T lymphocytes overcomes the monocyte dependency of pokeweed mitogen-induced T-cell activation.

Activation of T lymphocytes by pokeweed mitogen (PWM) is strictly monocyte (Mo)-dependent and results in T-cell mitogenesis and interleukin-2 (IL-2) secretion, coupled with an inability to utilize IL-2 due to an impaired expression of functional IL-2 receptor (IL-2R). Such IL-2R impairment could ari...

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Hlavní autoři: Gallart, T, Angel de la Fuente, M, Josep Barceló, J, Alberola-Ila, J, Lozano, F
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456722/
https://ncbi.nlm.nih.gov/pubmed/9038713
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