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Involvement of Stat3 in interleukin-6-induced IgM production in a human B-cell line.

Interleukin-6 (IL-6) is an important B-cell growth and differentiation factor. IL-6 treatment of the human lymphoblastoid cell line, SKW6.4, leads to increased IgM production. We have previously shown that IL-6 induces activation of JAK1 and JAK2 in human B cell lines. A chimeric IL-6 receptor, comp...

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Библиографические подробности
Главные авторы: Faris, M, Kokot, N, Stahl, N, Nel, A E
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456618/
https://ncbi.nlm.nih.gov/pubmed/9155640
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