Alloantigen-specific T-cell anergy induced by human keratinocytes is abrogated upon loss of cell-cell contact.

The activation of primary human T cells largely depends on the expression of both major histocompatibility complex (MHC) class II and B7 molecules on antigen-presenting cells (APC), whereas APC expressing HLA class II but not B7 antigens are expected to induce anergy. According to this concept, inte...

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Detalhes bibliográficos
Main Authors: Otten, H G, Bor, B, Ververs, C, Verdonck, L F, De Boer, M, De Gast, G C
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456420/
https://ncbi.nlm.nih.gov/pubmed/8690453
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