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Mutations in the extra sex combs and Enhancer of Polycomb Genes Increase Homologous Recombination in Somatic Cells of Drosophila melanogaster

We found that heterozygous mutant alleles of E(Pc) and esc increased homologous recombination from an allelic template in somatic cells in a P-element-induced double-strand break repair assay. Flies heterozygous for mutant alleles of these genes showed increased genome stability and decreased levels...

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Detalhes bibliográficos
Main Authors: Holmes, Angela M., Weedmark, Kelly A., Gloor, Gregory B.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456408/
https://ncbi.nlm.nih.gov/pubmed/16452150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.042473
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