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Functions of Multiple Exonucleases Are Essential for Cell Viability, DNA Repair and Homologous Recombination in recD Mutants of Escherichia coli
Heterotrimeric RecBCD enzyme unwinds and resects a DNA duplex containing blunt double-stranded ends and directs loading of the strand-exchange protein RecA onto the unwound 3′-ending strand, thereby initiating the majority of recombination in wild-type Escherichia coli. When the enzyme lacks its Rec...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456380/ https://ncbi.nlm.nih.gov/pubmed/16452142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052076 |
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