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Positive Selection Can Create False Hotspots of Recombination
Simulations of positive directional selection, under parameter values appropriate for approximating human genetic diversity and rates of recombination, reveal that the effects of strong selective sweeps on patterns of linkage disequilibrium (LD) mimic the pattern expected with recombinant hotspots.
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Copyright © 2006 by the Genetics Society of America
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456281/ https://ncbi.nlm.nih.gov/pubmed/16387873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052183 |
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