The Role of Selection in the Evolution of Human Mitochondrial Genomes

High mutation rate in mammalian mitochondrial DNA generates a highly divergent pool of alleles even within species that have dispersed and expanded in size recently. Phylogenetic analysis of 277 human mitochondrial genomes revealed a significant (P < 0.01) excess of rRNA and nonsynonymous base su...

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Main Authors: Kivisild, Toomas, Shen, Peidong, Wall, Dennis P., Do, Bao, Sung, Raphael, Davis, Karen, Passarino, Giuseppe, Underhill, Peter A., Scharfe, Curt, Torroni, Antonio, Scozzari, Rosaria, Modiano, David, Coppa, Alfredo, de Knijff, Peter, Feldman, Marcus, Cavalli-Sforza, Luca L., Oefner, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: Copyright © 2006 by the Genetics Society of America 2006
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456165/
https://ncbi.nlm.nih.gov/pubmed/16172508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.043901
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