Nuclear–Mitochondrial Epistasis and Drosophila Aging: Introgression of Drosophila simulans mtDNA Modifies Longevity in D. melanogaster Nuclear Backgrounds

Under the mitochondrial theory of aging, physiological decline with age results from the accumulated cellular damage produced by reactive oxygen species generated during electron transport in the mitochondrion. A large body of literature has documented age-specific declines in mitochondrial function...

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Bibliografiske detaljer
Main Authors: Rand, David M., Fry, Adam, Sheldahl, Lea
Format: Artigo
Sprog:Inglês
Udgivet: Copyright © 2006 by the Genetics Society of America 2006
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456161/
https://ncbi.nlm.nih.gov/pubmed/16219776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.046698
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