Schizosaccharomyces pombe Adenylate Cyclase Suppressor Mutations Suggest a Role for cAMP Phosphodiesterase Regulation in Feedback Control of Glucose/cAMP Signaling

Mutations affecting the Schizosaccharomyces pombe cAMP phosphodiesterase (PDE) gene cgs2(+) were identified in a screen for suppressors of mutant alleles of the adenylate cyclase gene (git2(+)/cyr1(+)), which encode catalytically active forms of the enzyme that cannot be stimulated by extracellular...

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Autores principales: Wang, Lili, Griffiths, Kenneth, Zhang, Y. Hi, Ivey, F. Douglas, Hoffman, Charles S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright © 2005 by the Genetics Society of America 2005
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Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456081/
https://ncbi.nlm.nih.gov/pubmed/16143612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.047233
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