Functional Connection Between the Clb5 Cyclin, the Protein Kinase C Pathway and the Swi4 Transcription Factor in Saccharomyces cerevisiae

The rsf12 mutation was isolated in a synthetic lethal screen for genes functionally interacting with Swi4. RSF12 is CLB5. The clb5 swi4 mutant cells arrest at G(2)/M due to the activation of the DNA-damage checkpoint. Defects in DNA integrity was confirmed by the increased rates of chromosome loss a...

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Main Authors: Queralt, Ethel, Igual, J. Carlos
פורמט: Artigo
שפה:Inglês
יצא לאור: Copyright © 2005 by the Genetics Society of America 2005
נושאים:
Investigations
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456078/
https://ncbi.nlm.nih.gov/pubmed/16118191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.045005
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