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Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme
The crystal structure of biotin synthase from Escherichia coli in complex with S-adenosyl-l-methionine and dethiobiotin has been determined to 3.4 angstrom resolution. This structure addresses how “AdoMet radical” or “radical SAM” enzymes use Fe(4)S(4) clusters and S-adenosyl-l-methionine to generat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456065/ https://ncbi.nlm.nih.gov/pubmed/14704425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1088493 |
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