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Microelectrode array recordings of cultured hippocampal networks reveal a simple model for transcription and protein synthesis-dependent plasticity

A simplified cell culture system was developed to study neuronal plasticity. As changes in synaptic strength may alter network activity patterns, we grew hippocampal neurones on a microelectrode array (MEA) and monitored their collective behaviour with 60 electrodes simultaneously. We found that exp...

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Detalhes bibliográficos
Main Authors: Arnold, Fiona JL, Hofmann, Frank, Bengtson, C. Peter, Wittmann, Malte, Vanhoutte, Peter, Bading, Hilmar
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456059/
https://ncbi.nlm.nih.gov/pubmed/15618268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077446
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