Human DNA polymerase β initiates DNA synthesis during long-patch repair of reduced AP sites in DNA

Simple base damages are repaired through a short-patch base excision pathway where a single damaged nucleotide is removed and replaced. DNA polymerase β (Pol β) is responsible for the repair synthesis in this pathway and also removes a 5′-sugar phosphate residue by catalyzing a β-elimination reactio...

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izdano v:	EMBO J
Principais autores:	Podlutsky, Andrej Ja., Dianova, Irina I., Podust, Vladimir N., Bohr, Vilhelm A., Dianov, Grigory L.
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2001
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145539/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11250913/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.6.1477
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