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Cross-talk between catalytic and regulatory elements in a DEAD motor domain is essential for SecA function

SecA, the motor subunit of bacterial polypeptide translocase, is an RNA helicase. SecA comprises a dimerization C-terminal domain fused to an ATPase N-terminal domain containing conserved DEAD helicase motifs. We show that the N-terminal domain is organized like the motor core of DEAD proteins, enco...

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Hlavní autoři: Sianidis, Georgios, Karamanou, Spyridoula, Vrontou, Eleftheria, Boulias, Kostantinos, Repanas, Kostantinos, Kyrpides, Nikos, Politou, Anastasia S., Economou, Anastassios
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC145479/
https://ncbi.nlm.nih.gov/pubmed/11230120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.5.961
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