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Failure of affinity maturation leads to increased susceptibility to immune complex glomerulonephritis.

Mice, previously selected for the production of low affinity antibody after four injections of protein antigens in saline, fell into two groups on the basis of their antibody response after injection of adjuvantized antigen. One group produced antibody of sequentially rising affinity but the other p...

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Detalhes bibliográficos
Main Authors: Devey, M E, Bleasdale, K, Stanley, C, Steward, M W
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1454625/
https://ncbi.nlm.nih.gov/pubmed/6234231
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