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Immunological tolerance to a non-cytopathic virus is not inheritable in mice.

Male lymphocytic choriomeningitis (LCM) virus-carrier mice were mated to uninfected females and their offsprings tested for (i) LCMV virus and (ii) their potential to generate LCM virus-specific cytotoxic T cells. Among about 500 offspring tested no example of antigen-independent inheritance of tole...

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Bibliographic Details
Main Authors: Stitz, L, Zinkernagel, R M
Format: Artigo
Language:Inglês
Published: 1984
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1454617/
https://ncbi.nlm.nih.gov/pubmed/6203830
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