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Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways

Neurotrophins (NTs) play an essential role in modulating activity-dependent neuronal plasticity. In this context, the site and extent of NT secretion are of crucial importance. Here, we demonstrate that the activation of phospolipase C (PLC) and the subsequent mobilization of Ca(2+) from intracellul...

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Detalhes bibliográficos
Main Authors: Canossa, Marco, Gärtner, Annette, Campana, Gabriele, Inagaki, Naoyuki, Thoenen, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145457/
https://ncbi.nlm.nih.gov/pubmed/11285228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1640
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