A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG

Alternative splicing is one of the central mechanisms that regulate eukaryotic gene expression. Here we report a tissue-specific RNA-binding protein, Fox-1, which regulates alternative splicing in vertebrates. Fox-1 bound specifically to a pentanucleotide GCAUG in vitro. In zebrafish and mouse, fox-...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Jin, Yui, Suzuki, Hitoshi, Maegawa, Shingo, Endo, Hitoshi, Sugano, Sumio, Hashimoto, Katsuyuki, Yasuda, Kunio, Inoue, Kunio
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145449/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574126/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg089
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