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Stimulation of macrophage protease secretion via liposomal delivery of muramyl dipeptide derivatives to intracellular sites.

We have observed that murine macrophages can be activated for enhanced neutral protease secretion by exposing the cells to muramyl dipeptides (MDPs). A lipophilic derivative of nor-MDP is more efficacious than the parent hydrophilic nor-MDP. The efficacy and potency of the lipophilic and more promin...

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Bibliographic Details
Main Authors: Mehta, K, Juliano, R L, Lopez-Berestein, G
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1454456/
https://ncbi.nlm.nih.gov/pubmed/6365745
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