Immunological responses to fed protein antigens in mice. II. Oral tolerance for CMI is due to activation of cyclophosphamide-sensitive cells by gut-processed antigen.

Mice fed ovalbumin develop specific systemic hyporesponsiveness. This oral tolerance is abrogated by cyclophosphamide pretreatment, and the mechanism of abrogation could be either via T suppressor cells or via damage to the gut epithelium. A serum transfer protocol was used to examine the site of ac...

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Detalhes bibliográficos
Main Authors: Strobel, S, Mowat, A M, Drummond, H E, Pickering, M G, Ferguson, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1454306/
https://ncbi.nlm.nih.gov/pubmed/6862521
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