Ectopic HP1 promotes chromosome loops and variegated silencing in Drosophila

A transgene inserted in euchromatin exhibits mosaic expression when targeted by a fusion protein made of the DNA-binding domain of GAL4 and the heterochromatin-associated protein HP1. The silencing responds to the loss of a dose of the dominant modifiers of position-effect variegation Su(var)3-7 and...

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Publicat a:	EMBO J
Autors principals:	Seum, Carole, Delattre, Marion, Spierer, Anne, Spierer, Pierre
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2001
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11179225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.4.812
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