Cyclosporin A inhibits lymphokine production but not the responses of macrophages to lymphokines.

Cyclosporin A (Cs A) exerted a dose-related inhibitory effect on antigen (ovalbumin, OVA) and phytohaemagglutinin (PHA)-induced transformation of guinea-pig lymph node cells (LNC). Whereas 0.05 micrograms/ml was sufficient to depress these responses markedly, it required 100-fold this concentration...

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Bibliographic Details
Main Authors: Thomson, A W, Moon, D K, Geczy, C L, Nelson, D S
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453909/
https://ncbi.nlm.nih.gov/pubmed/6337088
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