Different pathways of human T-cell activation revealed by PHA-P and PHA-M.

Antigen-specific T-cell activation is mediated via the CD3-Ti (antigen receptor) complex, and monoclonal antibodies to both CD3 and Ti cause a rapid rise in intracellular Ca2+. This calcium mobilization is not inhibited by monoclonal antibodies to CD2. The rise in calcium mobilization induced by pur...

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Bibliografiske detaljer
Main Authors: O'Flynn, K, Russul-Saib, M, Ando, I, Wallace, D L, Beverley, P C, Boylston, A W, Linch, D C
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453876/
https://ncbi.nlm.nih.gov/pubmed/2417941
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