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Vaccine-Induced Reduction of Helicobacter pylori Colonization in Mice Is Interleukin-12 Dependent but Gamma Interferon and Inducible Nitric Oxide Synthase Independent

Previous studies with mice have shown that major histocompatibility complex class II (MHC-II) is required for protection from Helicobacter pylori, while MHC-I and antibodies are not. Thus, CD4(+) T cells are presumed to play an essential role in protective immunity via secretion of cytokines. To det...

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Main Authors: Garhart, Christine A., Heinzel, Frederick P., Czinn, Steven J., Nedrud, John G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC145373/
https://ncbi.nlm.nih.gov/pubmed/12540573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.2.910-921.2003
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