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The activation of C5 in the fluid phase and in the absence of C3 through the classical pathway of the complement system.

Unsensitized guinea-pig erythrocytes (Egp) were lysed by a combination of eight isolated, human-derived complement components, Cls, C4, C2, C5, C6, C7, C8 and C9 (Cls-C9exC3), even in the presence of anti-C3. It was determined that a factor was generated in the reaction mixture of Cls, C4, C2, C5 an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kitamura, H, Tsuboi, M, Nagaki, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453482/
https://ncbi.nlm.nih.gov/pubmed/3733147
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