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Inhibition of human monocyte respiratory burst, degranulation, phospholipid methylation and bactericidal activity by pneumolysin.

The interaction between the pneumococcal toxin pneumolysin and human monocytes was examined. At non-cytotoxic concentrations (0.5-2.5 HU/10(6) cells) pneumolysin depressed the oxygen-dependent respiratory burst in monocytes, induced by opsonized zymosan or phorbol myristate acetate (PMA). This inclu...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Nandoskar, M, Ferrante, A, Bates, E J, Hurst, N, Paton, J C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1986
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453333/
https://ncbi.nlm.nih.gov/pubmed/3804376
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