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Silica decreases phagocytosis and bactericidal activity of both macrophages and neutrophils in vitro.

Silica, or silicon dioxide, has been shown to be toxic for macrophages. This is probably because it damages phagolysosomal membranes, allowing lysosomal enzymes to disrupt the cell. Neutrophils also take up particles such as silica and in addition they contain lysosomes. The purpose of this study wa...

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Detalhes bibliográficos
Main Authors: Zimmerman, B T, Canono, B P, Campbell, P A
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453318/
https://ncbi.nlm.nih.gov/pubmed/3026960
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