Cyclophosphamide-induced eosinophilia in the rat: concomitant changes in T-cell subsets, B cells and large granular lymphocytes within lymphoid tissues.

Cyclophosphamide (Cy) treatment (150 mg/kg) of Sprague-Dawley rats 48 hr before immunization with a T-dependent antigen, ovalbumin (OVA), resulted in striking bone marrow, blood and tissue eosinophilia, maximal at 14 days and concurrent with profound lymphopenia. This phenomenon has been tentatively...

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Main Authors: Thomson, A W, Mathie, I H, Sewell, H F
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453252/
https://ncbi.nlm.nih.gov/pubmed/3494668
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