Production and characterization of pepsin fragments of human IgA1 to determine domain-specificity of monoclonal anti-IgA antibodies.

Eight human IgA1 myeloma proteins were analysed by SDS-PAGE. These experiments showed that purified IgA1 proteins comprise both fully S-S bonded and partly S-S bonded molecules. Pepsin digestion of the IgA1 proteins yielded three four-chain and two two-chain fragments. The four-chain fragments are l...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Biewenga, J, Faber, A, Pronk, J C, Haaijman, J J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1986
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1453135/
https://ncbi.nlm.nih.gov/pubmed/3093370
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