Accumulation of S-Adenosyl-l-Methionine Enhances Production of Actinorhodin but Inhibits Sporulation in Streptomyces lividans TK23

S-Adenosyl-l-methionine synthetase (SAM-s) catalyzes the biosynthesis of SAM from ATP and l-methionine. Despite extensive research with many organisms, its role in Streptomyces sp. remains unclear. In the present study, the putative SAM-s gene was isolated from a spectinomycin producer, Streptomyces...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Kim, Dong-Jin, Huh, Jung-Hyun, Yang, Young-Yell, Kang, Choong-Min, Lee, In-Hyung, Hyun, Chang-Gu, Hong, Soon-Kwang, Suh, Joo-Won
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Gene Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12511506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.2.592-600.2003
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