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HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway

Genetic deficiency or inhibition of cholesteryl ester transfer protein (CETP) leads to a marked increase in plasma levels of large HDL-2 particles. However, there is concern that such particles may be dysfunctional in terms of their ability to promote cholesterol efflux from macrophages. Recently, t...

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Detalhes bibliográficos
Main Authors: Matsuura, Fumihiko, Wang, Nan, Chen, Wengen, Jiang, Xian-Cheng, Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1451209/
https://ncbi.nlm.nih.gov/pubmed/16670775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27602
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