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The Rate of Compensatory Mutation in the DNA Bacteriophage φX174

A compensatory mutation occurs when the fitness loss caused by one mutation is remedied by its epistatic interaction with a second mutation at a different site in the genome. This poorly understood biological phenomenon has important implications, not only for the evolutionary consequences of mutati...

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Detalhes bibliográficos
Main Authors: Poon, Art, Chao, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1451187/
https://ncbi.nlm.nih.gov/pubmed/15911582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039438
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