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Toward a Neutral Evolutionary Model of Gene Expression

We introduce a stochastic model that describes neutral changes of gene expression over evolutionary time as a compound Poisson process where evolutionary events cause changes of expression level according to a given probability distribution. The model produces simple estimators for model parameters...

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Autori principali: Khaitovich, Philipp, Pääbo, Svante, Weiss, Gunter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450413/
https://ncbi.nlm.nih.gov/pubmed/15834146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.037135
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