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PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma

BACKGROUND: Although PPARγ antagonists have shown considerable pre-clinical efficacy, recent studies suggest PPARγ ligands induce PPARγ-independent effects. There is a need to better define such effects to permit rational utilization of these agents. METHODS: We have studied the effects of a range o...

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Autori principali: Chaffer, Christine L, Thomas, David M, Thompson, Erik W, Williams, Elizabeth D
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450298/
https://ncbi.nlm.nih.gov/pubmed/16519808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-53
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