A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample

The dopamine (DA) transporter DAT1 is a major target bound by cocaine in brain. We examined the influence of functional genetic variants in DAT1 on cocaine addiction. Repeat polymorphisms, including a 30-bp variable-number tandem repeat (VNTR) in intron 8 (Int8 VNTR) with two common alleles, were ge...

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Hlavní autoři: Guindalini, Camila, Howard, Mark, Haddley, Kate, Laranjeira, Ronaldo, Collier, David, Ammar, Nik, Craig, Ian, O’Gara, Colin, Bubb, Vivian J., Greenwood, Tiffany, Kelsoe, John, Asherson, Phil, Murray, Robin M., Castelo, Adauto, Quinn, John P., Vallada, Homero, Breen, Gerome
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450209/
https://ncbi.nlm.nih.gov/pubmed/16537431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504789103
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