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Self-catalyzed site-specific depurination of guanine residues within gene sequences

A self-catalyzed, site-specific guanine-depurination activity has been found to occur in short gene sequences with a potential to form a stem-loop structure. The critical features of that catalytic intermediate are a 5′-G-T-G-G-3′ loop and an adjacent 5′-T·A-3′ base pair of a short duplex stem stabl...

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Detalhes bibliográficos
Main Authors: Amosova, Olga, Coulter, Richard, Fresco, Jacques R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450182/
https://ncbi.nlm.nih.gov/pubmed/16537362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508499103
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