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Signals from OX40 regulate nuclear factor of activated T cells c1 and T cell helper 2 lineage commitment
T cell helper type 2 (Th2) differentiation is driven by a source of IL-4 receptor (IL-4R) that mobilizes IL-4R signaling pathways and the transcription factor GATA-3. Naïve CD4 cells can secrete IL-4 independently of IL-4R signals, but how this secretion is regulated is not understood. Here we demon...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450148/ https://ncbi.nlm.nih.gov/pubmed/16501042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600205103 |
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