Constitutive expression of the Period1 gene impairs behavioral and molecular circadian rhythms

Three mammalian Period (Per) genes, termed Per1, Per2, and Per3, have been identified as structural homologues of the Drosophila circadian clock gene, period (per). The three Per genes are rhythmically expressed in the suprachiasmatic nucleus (SCN), the central circadian pacemaker in mammals. The ph...

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Detalhes bibliográficos
Main Authors: Numano, Rika, Yamazaki, Shin, Umeda, Nanae, Samura, Tomonori, Sujino, Mitsugu, Takahashi, Ri-ichi, Ueda, Masatsugu, Mori, Akiko, Yamada, Kazunori, Sakaki, Yoshiyuki, Inouye, Shin-Ichi T., Menaker, Michael, Tei, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450145/
https://ncbi.nlm.nih.gov/pubmed/16537451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600060103
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