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Projection structure of the human copper transporter CTR1 at 6-Å resolution reveals a compact trimer with a novel channel-like architecture
Human CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6-Å projection structure obtained for human CTR1 by using electron crystallography of 2D protein crystals in a native phospholip...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450133/ https://ncbi.nlm.nih.gov/pubmed/16501047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509929103 |
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