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Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptide

Studies in vitro have established that free tryptophan induces tna operon expression by binding to the ribosome that has just completed synthesis of TnaC-tRNA(Pro), the peptidyl-tRNA precursor of the leader peptide of this operon. Tryptophan acts by inhibiting Release Factor 2-mediated cleavage of t...

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Autors principals: Cruz-Vera, Luis Rogelio, Gong, Ming, Yanofsky, Charles
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450129/
https://ncbi.nlm.nih.gov/pubmed/16505360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600082103
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