Maternal Transmission Ratio Distortion at the Mouse Om Locus Results From Meiotic Drive at the Second Meiotic Division

We have observed maternal transmission ratio distortion (TRD) in favor of DDK alleles at the Ovum mutant (Om) locus on mouse chromosome 11 among the offspring of (C57BL/6 × DDK) F(1) females and C57BL/6 males. Although significant lethality occurs in this backcross (∼50%), differences in the level o...

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Bibliografiske detaljer
Main Authors: Wu, Guangming, Hao, Lanping, Han, Zhiming, Gao, Shaorong, Latham, Keith E., de Villena, Fernando Pardo-Manuel, Sapienza, Carmen
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2005
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449735/
https://ncbi.nlm.nih.gov/pubmed/15744049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039479
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