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Highly designable phenotypes and mutational buffers emerge from a systematic mapping between network topology and dynamic output

Deciphering the design principles for regulatory networks is fundamental to an understanding of biological systems. We have explored the mapping from the space of network topologies to the space of dynamical phenotypes for small networks. Using exhaustive enumeration of a simple model of three- and...

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Detalhes bibliográficos
Main Authors: Nochomovitz, Yigal D., Li, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449667/
https://ncbi.nlm.nih.gov/pubmed/16537505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507032103
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