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Optimizing the Nucleotide Sequence of a Meiotic Recombination Hotspot in Schizosaccharomyces pombe

The ade6-M26 mutation of Schizosaccharomyces pombe created a meiotic recombination hotspot. Previous analyses indicated that the heptamer 5′-ATGACGT-3′ was necessary and sufficient for hotspot activity; the Atf1-Pcr1 transcription factor binds to this sequence and activates M26. After finding cases...

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Detalhes bibliográficos
Main Authors: Steiner, Walter W., Smith, Gerald R.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449614/
https://ncbi.nlm.nih.gov/pubmed/15716492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039230
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