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A Genetic Screen for top3 Suppressors in Saccharomyces cerevisiae Identifies SHU1, SHU2, PSY3 and CSM2: Four Genes Involved in Error-Free DNA Repair

Helicases of the RecQ family and topoisomerase III are evolutionarily conserved proteins important for maintenance of genome stability. In Saccharomyces cerevisiae, loss of the TOP3 gene, encoding topoisomerase III, results in a phenotype of slow growth, DNA damage sensitivity, meiotic defects, and...

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Detalhes bibliográficos
Main Authors: Shor, Erika, Weinstein, Justin, Rothstein, Rodney
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449555/
https://ncbi.nlm.nih.gov/pubmed/15654096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.036764
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