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Chromosome Loss Followed by Duplication Is the Major Mechanism of Spontaneous Mating-Type Locus Homozygosis in Candida albicans
Candida albicans, which is diploid, possesses a single mating-type (MTL) locus on chromosome 5, which is normally heterozygous (a/α). To mate, C. albicans must undergo MTL homozygosis to a/a or α/α. Three possible mechanisms may be used in this process, mitotic recombination, gene conversion, or los...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Genetics Society of America
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449533/ https://ncbi.nlm.nih.gov/pubmed/15654090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.033167 |
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