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Long-Term Experimental Evolution in Escherichia coli. XII. DNA Topology as a Key Target of Selection

The genetic bases of adaptation are being investigated in 12 populations of Escherichia coli, founded from a common ancestor and serially propagated for 20,000 generations, during which time they achieved substantial fitness gains. Each day, populations alternated between active growth and nutrient...

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Main Authors: Crozat, Estelle, Philippe, Nadège, Lenski, Richard E., Geiselmann, Johannes, Schneider, Dominique
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449116/
https://ncbi.nlm.nih.gov/pubmed/15489515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.035717
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