Lig4 and Rad54 Are Required for Repair of DNA Double-Strand Breaks Induced by P-Element Excision in Drosophila

Site-specific double-strand breaks (DSBs) were generated in the white gene located on the X chromosome of Drosophila by excision of the w(hd) P-element. To investigate the role of nonhomologous end joining (NHEJ) and homologous recombination (HR) in the repair of these breaks, the w(hd) P-element wa...

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Bibliographic Details
Main Authors: Romeijn, Ron J., Gorski, Marcin M., van Schie, Martijn A., Noordermeer, Jasprina N., Mullenders, Leon H., Ferro, Wouter, Pastink, Albert
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2005
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449100/
https://ncbi.nlm.nih.gov/pubmed/15545651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.033464
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